What is TB-500?
TB-500 is a synthetic version of the natural peptide thymosin beta-4, which is found in almost all tissues of the human body. It is made up of 43 amino acids and has been described in research models with a potential role in the processes of cell migration, angiogenesis and tissue repair. In research models, TB-500 has been described with the potential to support tissue regeneration, inflammatory response and healing processes. In research settings, it has shown effects on improving the healing of tendons, muscles and skin.
Observations on TB-500
TB-500 is being studied for its possible effects on:
Healing of muscle and tendon injuries – in research models, an effect on repair processes and tissue regeneration has been observed.
Stimulation of angiogenesis – a described effect on the formation of new blood vessels and local blood supply.
Anti-inflammatory effect – observed influence on inflammatory mediators and edema.
Joint and bone health – in research settings, an effect on recovery processes after injuries has been described.
Healing of skin and connective tissue lesions – an effect on the regeneration of epithelial tissues has been observed in research models.
Scientific data
TB-500 has been studied primarily in preclinical models, but also in some clinical experiments.
In orthopedics, it has shown potential for improved healing of tendon and muscle tears, as well as accelerated recovery after surgery.
In cardiology, there is evidence of a protective effect in myocardial damage by stimulating angiogenesis and improved local blood supply.
In neurology, experiments show that it can help restore nerve cells and reduce damage after ischemic incidents.
In dermatology, faster healing of skin wounds and ulcers has been reported.
Dosage and administration
In the scientific literature, subcutaneous administration of doses of 2-5 mg, administered 3 times a week for 4-6 weeks, is most commonly found, followed by a maintenance phase.
At 5 mg + 3 ml bacteriostatic water: 1.67 mg/ml → 0.3 ml = 0.5 mg
At 10 mg + 3 ml bacteriostatic water: 3.3 mg/ml → 0.3 ml = 1 mg
Example values for 5 mg:
0.15 ml = 250 μg
0.3 ml = 500 μg
0.45 ml = 750 μg
0.6 ml = 1 mg
0.75 ml = 1.25 mg
Example values for 10 mg:
0.15 ml = 500 μg
0.3 ml = 1 mg
0.45 ml = 1.5 mg
Application in sports
TB-500 is banned by WADA for use by athletes because it may:
- accelerate recovery after muscle and tendon injuries
- improve blood supply and tissue healing
- shorten recovery time between intense workouts
Possible side effects
Reported side effects are rare and usually mild:
- fatigue
- headache
- redness or pain at the injection site
Less commonly, changes in appetite or drowsiness may be observed.
The information has been collected and systematized from various scientific sources and studies. It serves educational purposes only and should not be used for the diagnosis, treatment or prevention of diseases .