What is GHRP-2?
GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide that acts as an agonist of the ghrelin receptor (GHS-R1a). It stimulates the pituitary gland to secrete growth hormone (GH) and is one of the first members of the GHRP family to be developed. GHRP-2 is being actively studied for its potential effects on muscle growth, recovery, and metabolism. Compared to GHRP-6, GHRP-2 has a stronger effect on GH secretion and is more selective. It is being studied in research settings for its effects on muscle growth, tissue repair, and metabolic processes. In research models, it has been observed to have an effect on anabolism, bone health, and lipolysis, while simultaneously promoting deep sleep and appetite.
Observations on GHRP-2
GHRP-2 is being studied for its possible effects on:
- Growth hormone stimulation - enhances GH pulses and is associated with increases in IGF-1
- Increase muscle mass - supports protein synthesis and anabolic processes
- Improved recovery - accelerates regeneration after physical exertion
- Joint and bone health - improves mineralization and repair of connective tissues
- Fat reduction - stimulates lipolysis and metabolic balance
- Anti-aging effects - supports GH secretion in old age
- Appetite-stimulating effect - activates ghrelin receptors and increases food intake
Scientific data
In the scientific literature, GHRP-2 has been extensively studied in preclinical and clinical models. It has been found that the peptide induces a dose-dependent increase in growth hormone (GH) and insulin-like growth factor-1 (IGF-1) by activating GHS-R1a receptors , stimulating endogenous GH release.
Among the GHRP peptides, GHRP-2 is distinguished by its high efficacy and stability , making it interesting for research in endocrinology, gerontology, and sports medicine . Some studies have noted that at higher doses it can lead to moderate increases in cortisol and prolactin , which emphasizes the importance of careful dosing in experimental settings.
Dosage and administration
The scientific literature describes subcutaneous administration of 100-300 μg daily, divided into 1-3 applications.
At 5 mg + 3 ml bacteriostatic water:
Concentration = 1.67 mg/ml → 0.15 ml = 250 μg
At 10 mg + 3 ml bacteriostatic water:
Concentration = 3.3 mg/ml → 0.15 ml = 500 μg
Example values for 5 mg:
0.06 ml = 100 μg
0.12 ml = 200 μg
0.18 ml = 300 μg
0.24 ml = 400 μg
Example values for 10 mg:
0.06 ml = 200 μg
0.12 ml = 400 μg
0.18 ml = 600 μg
0.24 ml = 800 μg
Application in sports
GHRP-2 is banned by WADA for use in professional sports because it can:
- Stimulates the secretion of growth hormone
- Accelerate tissue repair
- Promote muscle growth and strength
- Reduces recovery time after exertion
Possible side effects
Side effects are usually dose-related and include:
- Redness or pain at the injection site
- Fatigue or drowsiness
- Increased appetite
- Fluid retention
- Increased cortisol and prolactin levels at higher doses
Less commonly, headache or dizziness have been reported.
The information has been collected and systematized from various scientific sources and studies. It serves educational purposes only and should not be used for the diagnosis, treatment or prevention of diseases .